Clinical Endocrinology News RSS feed: Current Issue. http://www.clinicalendocrinologynews.com/?rss=yesElsevier Inc.en © 2012 Elsevier Inc. All rights reserved. Clinical Endocrinology News1558-016471January 2012 © 2012 Elsevier Inc. All rights reserved. healthpermissions@elsevier.comhttp://www.clinicalendocrinologynews.com/article/PIIS1558016412700019/abstract?rss=yesAll patients admitted to the hospital in noncritical care settings should have their blood glucose tested, according to a new clinical practice guideline from the Endocrine Society.Blood Glucose Testing for All Inpatients, Group SaysMIRIAM E. TUCKER10.1016/S1558-0164(12)70001-9Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9News12http://www.clinicalendocrinologynews.com/article/PIIS1558016412700020/abstract?rss=yesMedicare payments for the use of dual-energy x-ray absorptiometry are set to drop on March 1 unless Congress acts to extend the current payment rates for the screening procedure.DXA Payments Slated to Plummet March 1Mary Ellen Schneider10.1016/S1558-0164(12)70002-0Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9News11http://www.clinicalendocrinologynews.com/article/PIIS1558016412700032/abstract?rss=yes Major Finding: Cyclical natural progesterone therapy decreased seizure frequency by up to 71%, compared with placebo, in women with a high number of perimenstrual seizures.Progesterone Quells Some Catamenial SeizuresMICHELE G. SULLIVAN10.1016/S1558-0164(12)70003-2Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9News33http://www.clinicalendocrinologynews.com/article/PIIS1558016412700044/abstract?rss=yes Major Finding: A total of 43% of teenage girls with polycystic ovary syndrome have concomitant nonalcoholic fatty liver disease.NAFLD Common in Teenage Girls With PCOSM. ALEXANDER OTTO10.1016/S1558-0164(12)70004-4Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9News33http://www.clinicalendocrinologynews.com/article/PIIS1558016412700056/abstract?rss=yesSAN ANTONIO – Diagnosis of diabetes within the prior 4 years was independently associated with breast cancer in a Swedish case-control study. Dr. Håkan Olsson reported on all 2,724 women diagnosed with breast cancer in southern Sweden during 2005-2007 and 20,542 matched controls. He and his coworkers were interested in how the malignancy is related to diabetes, obesity, and serum lipid levels.Recent Diabetes Tied to Breast Cancer RiskBRUCE JANCIN10.1016/S1558-0164(12)70005-6Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9News88http://www.clinicalendocrinologynews.com/article/PIIS1558016412700068/abstract?rss=yes Major Finding: A 12-week treatment regimen of 4 g/day of a purified formulation of EPA produced a 21.5% placebo-corrected cut in triglyceride levels in patients on statin treatment who began with a triglyceride level greater than 200 mg/dL and less than 500 mg/dL.Purified Fish Oil Cut Triglycerides by 21%MITCHEL L. ZOLER10.1016/S1558-0164(12)70006-8Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9News99http://www.clinicalendocrinologynews.com/article/PIIS155801641270007X/abstract?rss=yesThe Food and Drug Administration has issued draft guidance to assist investigators and manufacturers in the development of artificial pancreas device systems to treat type 1 diabetes.FDA Issues Artificial Pancreas GuidanceMIRIAM E. TUCKER10.1016/S1558-0164(12)70007-XClinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9News1010http://www.clinicalendocrinologynews.com/article/PIIS1558016412700081/abstract?rss=yes Major Finding: Ninety-seven percent of autotransplant patients in the most recent cohort (2006-2011) were alive at 1 year. At 5 years, 86%-88% of the earlier transplants patients were still alive. Twenty-year survival is 66%. Pancreatitis pain resolved in 80%-90% of patients overall.Islet Cell Autografts Relieve Chronic Pancreatitis PainALICIA AULT10.1016/S1558-0164(12)70008-1Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9News1010http://www.clinicalendocrinologynews.com/article/PIIS1558016412700093/abstract?rss=yesCHICAGO – Four months of a restricted-calorie diet produced lasting reductions in pericardial fat and improvements in left ventricular diastolic function in a study of obese adults with type 2 diabetes.Cutting Calories Yielded Lasting Cardiac BenefitSUSAN BIRK10.1016/S1558-0164(12)70009-3Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Diabetes1111http://www.clinicalendocrinologynews.com/article/PIIS155801641270010X/abstract?rss=yesPHILADELPHIA – Early, intensive treatment for type 1 diabetes with conventional therapy halves the long-term risk of developing an impaired glomerular filtration rate, the common pathway leading to end-stage kidney disease, Dr. Ian H. de Boer said at the meeting.Intensive Glycemic Control Protects KidneysDIANA MAHONEY10.1016/S1558-0164(12)70010-XClinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Diabetes1212http://www.clinicalendocrinologynews.com/article/PIIS1558016412700111/abstract?rss=yesSAN FRANCISCO – Health care providers should be aware that adult patients with diabetes have a sharply increased risk for chronic liver disease and should be counseled accordingly, advised investigators with the Centers for Disease Control and Prevention.Diabetes Quadruples Risk of Liver DiseaseSUSAN LONDON10.1016/S1558-0164(12)70011-1Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Diabetes1313http://www.clinicalendocrinologynews.com/article/PIIS1558016412700123/abstract?rss=yesCHICAGO – Metabolic syndrome is significantly more common in patients with psoriatic arthritis than in those with rheumatoid arthritis, data on nearly 2,000 adults show. Previous studies have suggested that metabolic syndrome is associated with “a state of chronic, low-grade inflammation,” said Dr. Asena Bahce-Altuntas of Albert Einstein College of Medicine in New York. “Since psoriatic arthritis [PsA] is characterized by inflammation of both skin and joints, we may be underestimating this cardiovascular risk in PsA,” she said at the meeting.Metabolic Syndrome Strikes Hard in Psoriatic PatientsHEIDI SPLETE10.1016/S1558-0164(12)70012-3Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Diabetes1313http://www.clinicalendocrinologynews.com/article/PIIS1558016412700135/abstract?rss=yesLISBON – Psoriasis and diabetes are expensive diseases, and patients with both conditions experience a synergistic increase in health care utilization and costs that is significantly greater than the incremental economic burden imposed by each disease individually.Comorbid Psoriasis Adds Hefty Economic BurdenBRUCE JANCIN10.1016/S1558-0164(12)70013-5Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Diabetes1313http://www.clinicalendocrinologynews.com/article/PIIS1558016412700147/abstract?rss=yesSAN FRANCISCO – The Mediterranean diet may be superior to the low-fat diet for decreasing hepatic fat and increasing insulin sensitivity in patients with nonalcoholic fatty liver disease, based on a small randomized crossover study conducted in Australia.Mediterranean Diet May Be Effective in NAFLDSUSAN LONDON10.1016/S1558-0164(12)70014-7Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Diabetes1617http://www.clinicalendocrinologynews.com/article/PIIS1558016412700159/abstract?rss=yes Major Finding: The metabolic syndrome resolved in 11 of 86 patients after CPAP therapy, compared with 1 of those same patients after sham therapy. The treatment also significantly improved systolic and diastolic BP; total, LDL, and non-HDL cholesterol; triglycerides; glycated hemoglobin; weight; and visceral and subcutaneous fat.CPAP Aids Metabolic Syndrome in Apnea PatientsMARY ANN MOON10.1016/S1558-0164(12)70015-9Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Obesity1818http://www.clinicalendocrinologynews.com/article/PIIS1558016412700160/abstract?rss=yesORLANDO – Although higher systolic blood pressure and LDL cholesterol are traditional risk factors for cardiovascular disease, each may have a different effect on the cerebrovascular and coronary systems.High Systolic BP and LDL Predict Different EventsNASEEM S. MILLER10.1016/S1558-0164(12)70016-0Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Obesity1818http://www.clinicalendocrinologynews.com/article/PIIS1558016412700172/abstract?rss=yesHOT SPRINGS, VA. – An analysis of a large database of bariatric surgery patients has found that those with metabolic syndrome had dramatic improvements in comorbidities but a slightly higher rate of adverse events after 90 days.Weigh Surgical Options for Metabolic SyndromeALICIA AULT10.1016/S1558-0164(12)70017-2Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Obesity1919http://www.clinicalendocrinologynews.com/article/PIIS1558016412700184/abstract?rss=yesSAN DIEGO – About one-quarter of patients referred to a group hematology practice had iron deficiency associated with gastric bypass surgery, a study has shown. In addition, 57% demonstrated symptoms of pica syndrome – a craving for and compulsive eating of nonfood substances such as ice and starch.Iron Deficiency ‘Unintended Consequence’ of Gastric BypassDOUG BRUNK10.1016/S1558-0164(12)70018-4Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Obesity1919http://www.clinicalendocrinologynews.com/article/PIIS1558016412700196/abstract?rss=yesSAN FRANCISCO – Factors that can be measured in the first few years of life can predict whether a child will develop nonalcoholic fatty liver disease (NAFLD) by adolescence, suggests a study presented at the meeting.Early Factors Can Predict NAFLD in AdolescenceSUSAN LONDON10.1016/S1558-0164(12)70019-6Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Obesity2020http://www.clinicalendocrinologynews.com/article/PIIS1558016412700202/abstract?rss=yesOvereating on a diet low in protein caused less weight gain than overeating on a normal- or high-protein diet – but most of the body mass gained was fat, rather than the leaner muscle mass created by high-protein overeating, according to a recent report.Low-Protein Diet May Cause Less Weight Gain, More FatMARY ANN MOON10.1016/S1558-0164(12)70020-2Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Obesity2020http://www.clinicalendocrinologynews.com/article/PIIS1558016412700214/abstract?rss=yes Major Finding: Patients with less than a 50% drop in intraoperative parathyroid hormone level (IOPTH) did not differ from those with a drop of greater than or equal to 50% in terms of age, gender, symptoms, presence of hypercalcemia, preoperative localization, or median size or weight of the gland. But patients with less than a 50% drop in IOPTH were more likely to have single adenomas.‘50% Rule’ May Not Apply in Subset of PatientsCAROLINE HELWICK10.1016/S1558-0164(12)70021-4Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Pituitary, Thyroid & Adrenal2222http://www.clinicalendocrinologynews.com/article/PIIS1558016412700226/abstract?rss=yesSAN ANTONIO – Bilateral oophorectomy in women younger than age 45 is associated with a subsequent doubled prevalence of osteoporosis and a similarly elevated rate of arthritis, compared with women with intact ovaries.Early Oophorectomy Linked to Osteoporosis and ArthritisBRUCE JANCIN10.1016/S1558-0164(12)70022-6Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Osteoporosis2323http://www.clinicalendocrinologynews.com/article/PIIS1558016412700238/abstract?rss=yesSAN DIEGO – Newer anticonvulsants do not appear to be associated with the reduced bone mineral density seen with traditional anticonvulsants, based on results from a retrospective Veterans Affairs study.New Anticonvulsants Did Not Impair Bone Density in VA StudyBRUCE JANCIN10.1016/S1558-0164(12)70023-8Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Osteoporosis2323http://www.clinicalendocrinologynews.com/article/PIIS155801641270024X/abstract?rss=yesSAN ANTONIO – A new meta-analysis of 16 studies challenges the notion that breast cancer risk is inversely related to serum vitamin D level. In 10 studies, vitamin D was measured before diagnosis of breast cancer; in the other 6 studies, blood samples were gathered for vitamin D measurement only after the diagnosis.Analysis Challenges Link Between Vitamin D Deficiency and CancerBruce Jancin10.1016/S1558-0164(12)70024-XClinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Osteoporosis2323http://www.clinicalendocrinologynews.com/article/PIIS1558016412700251/abstract?rss=yesTORONTO – Low vitamin D levels were linked with more psychotic features in mentally ill adolescents, in a small study. Studies have linked vitamin D deficiency with seasonal affective disorder, schizophrenia, and depression, Dr. Barbara L. Gracious of Ohio State University, Columbus, said at the meeting. She and her colleagues studied 104 consecutive teens seen for acute or partial hospital stays for psychiatric symptoms over an 18-month period. Patients' average age was 15, 27% were male, and 73% were white. Overall, 72% had low vitamin D levels (25-OHD levels less than 30 ng/mL), and 34% were vitamin D deficient (25-OHD levels less than 20 ng/mL). By comparison, 9% of a cohort of teens from the NHANES (National Health and Nutrition Survey) were vitamin D deficient, the researchers noted.Low Vitamin D Levels Tied to Psychotic Symptoms in TeensHeidi Splete10.1016/S1558-0164(12)70025-1Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Osteoporosis2323http://www.clinicalendocrinologynews.com/article/PIIS1558016412700263/abstract?rss=yesWASHINGTON – As a Senate committee held a hearing Dec. 15 on the continuing drug shortage problem, the Food and Drug Administration announced that it would require some manufacturers to give the agency early warning of an imminent shortage.FDA's Steps to Avert Shortages Under Scrutiny: FDA to require manufacturers of some drugs to give early warning of impending supply problems.ALICIA AULT10.1016/S1558-0164(12)70026-3Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Practice Trends2424http://www.clinicalendocrinologynews.com/article/PIIS1558016412700275/abstract?rss=yesPhysicians who support a single-payer health system are urging the federal government to reject the Institute of Medicine's recommendations for designing the benefits package to be offered in the state-based health insurance exchanges.Proposed Health Exchange Benefits ‘Skimpy,’ Providers SayMARY ELLEN SCHNEIDER10.1016/S1558-0164(12)70027-5Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Practice Trends2424http://www.clinicalendocrinologynews.com/article/PIIS1558016412700287/abstract?rss=yesElectronic prescribing is getting better, but challenges remain related to e-renewals, mail-order pharmacy connectivity, and pharmacy processing of e-prescriptions, based on survey results from 114 individuals involved in e-prescribing in 97 health care organizations.e-Prescribing Survey Pinpoints BottlenecksFRANCES CORREA10.1016/S1558-0164(12)70028-7Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Practice Trends2525http://www.clinicalendocrinologynews.com/article/PIIS1558016412700299/abstract?rss=yesHOT SPRINGS, VA. – Since tort reform in Texas, the number of lawsuits and associated costs have decreased, but patient complaints to the state medical board and board investigations of physicians have risen, according to an analysis presented at the meeting.Texas Tort Reform: More Complaints, Lower CostsALICIA AULT10.1016/S1558-0164(12)70029-9Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Practice Trends2525http://www.clinicalendocrinologynews.com/article/PIIS1558016412700305/abstract?rss=yesThe Physician Payments Sunshine Act, a provision of the Affordable Care Act, aims to bring transparency to the practice of pharmaceutical and device companies providing meals, gifts, and payments to physicians. It requires that these companies, as well as biologic manufacturers and medical suppliers, report any “payment or other transfer of value” of $10 or greater to physicians and teaching hospitals. The manufacturer must report alltpayments to a single physician if they reach $100 in aggregate value for a year. The Centers for Medicare and Medicaid Services released a proposed ruleonn December 2011 outlining how the disclosures would work. Drug and device manufacturers can hold off collecting information until the CMS issues a final rule later this year. Sine agency predicted that the first reports required under the Physician Payments Sunshine Act will be publicly available by Sept. 30, 2013.The Physician Payments Sunshine Act10.1016/S1558-0164(12)70030-5Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Implementing Health Reform2626http://www.clinicalendocrinologynews.com/article/PIIS1558016412700317/abstract?rss=yesAdolescents and young adults with diabetes are 6% more likely to drop out of school than are those without the disease, according to Health Affairs report. The disparity is similar to the difference in dropout rates seen between young people who have attention deficit–hyperactivity disorder and those without ADHD, the study showedaInyoung adults with diabetes can expect to earn $160,000 less in wages over their working lives, compared with adults without the condition, said the researchers at Yale University, New Haven, Conn. By age 30, a person with diabetes can expect to have a 10-percentage-point reduction in the likelihood of being employed – in part because of reduced education – and to earn $6,000 less each year, compared with peers who do not have diabetes, the researchers said.Policy & Practice: Want more health reform news? Subscribe to our podcast – search ‘Policy & Practice’ in the iTunes storeNaseem S. Miller10.1016/S1558-0164(12)70031-7Clinical Endocrinology News 7, 1 (2012)2012-01-01Clinical Endocrinology News2012-01-0171S1558-0164(12)X7001-9Section2626